Position Overview

Natera is building a category-defining Health Systems business that moves beyond the transactional “vendor” model into a true strategic partner for leading health systems. We aim to deeply integrate into EMRs, clinical decision support tools, research pipelines, and quality improvement programs — delivering population-scale precision medicine solutions that combine genomics, clinical data, and informatics.

The Head of Product Management, Health Systems will be the senior-most product leader in this business. This role demands a rare blend of technical and commercial expertise — someone who can walk into a CIO’s office, collaborate with an informatics team on HL7/FHIR data integrations, and then pivot to shaping a commercial value proposition for the C-suite. The ideal candidate has hands-on experience building and scaling clinico-genomic data platforms and working with large, complex real-world datasets in healthcare.

This leader will define, build, and launch a portfolio of software-enabled diagnostics, EMR-integrated services, and data-driven clinical tools that differentiate Natera as the health system partner of choice. They will work cross-functionally with engineering, medical, informatics, sales, and research teams — and directly with partner health systems — to make population-level genomic insights actionable at the point of care.

Key Responsibilities

Product Strategy & Vision

Translate the GM’s strategic vision into a cohesive, executable roadmap for Health Systems offerings, encompassing diagnostics, data services, EMR-integrated tools, and decision support.
Identify and prioritize opportunities to embed Natera into health system infrastructure, including:

EMR integration (Epic, Cerner, etc.)
Clinical decision support deployments
Large-scale clinico-genomic databases for quality metrics and value-based care programs
Biobanking and informatics partnerships

Build a defensible “moat” by creating solutions that are sticky, interoperable, and aligned with health system strategic goals.

Product Development & Execution

Oversee full product lifecycle: concept → development → launch → scaling → optimization. Additional focus will be on designing and integrating complex data architectures that combine genomics, clinical data, and outcomes.
Lead cross-disciplinary development teams, ensuring compliance with CLIA/CAP requirements and interoperability standards (HL7, FHIR).
Ensure solutions address both technical feasibility (data flows, integration wiring, informatics infrastructure) and commercial viability (business models, ROI).
Troubleshoot in-market adoption barriers and continuously improve product-market fit.

Market Engagement & Customer Integration

Serve as the primary product interface for key customer stakeholders:

Precision medicine program leaders
Health IT and informatics departments
Health system executives (CIO, CMIO, CTO, CEO/COO)

Partner with clinical, research, and informatics leaders to design pilots, research collaborations, and integration roadmaps.
Understand and navigate the informatics decision-making chain within large health systems.

Leadership & Team Building

Hire, mentor, and grow a team of product managers with deep expertise in diagnostics, software, and health systems.
Foster a metrics-driven, innovative product culture that thrives in a “big startup” environment — fast-moving, resourceful, and execution-focused.
Collaborate closely with internal sales, business development, and marketing to ensure consistent messaging, positioning, and enablement.

Business & Commercial Planning

Build business cases and define success metrics for new initiatives.
Shape go-to-market strategy in partnership with sales and marketing.
Lead due diligence for partnerships, licensing deals, and health system agreements.

Qualifications

10+ years in product management/product development in diagnostics, health tech, or medical software — with at least 7 years leading product teams.
Direct experience building and managing large clinico-genomic databases or equivalent real-world data platforms.
Strong background in bioinformatics, computational biology, data science, and engineering — with technical fluency to guide architecture decisions.
Proven success in launching diagnostic or software products into clinical settings with EMR integration and decision support.
Deep understanding of:

Genomics and clinical data interoperability
EMR systems (Epic, Cerner)
Healthcare system workflows
CLIA/CAP design control requirements

Experience in population health, value-based care models, and enterprise health system contracting.
Commercial acumen — able to translate technical capabilities into health system business value.

Personal Characteristics

Equal parts technical translator and business strategist.
Comfortable in C-suite settings and in technical deep-dives with informatics teams.
Hands-on leader who thrives in ambiguous, high-growth environments.
Customer-obsessed, collaborative, and outcomes-driven.
Strong communicator and relationship builder.

Why This Role Is Unique

Greenfield opportunity to shape how genomic and clinical data is integrated at scale in U.S. health systems.
Direct impact on Natera’s ability to shift from vendor to embedded partner in population health.
High visibility and cross-functional influence across engineering, medical, informatics, sales, and executive leadership.